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100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200
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KPV research vial
COA ON FILEMADE IN USA
Single Peptides

KPV

$59.99$6.00/mg
Size
Manufactured in the USA
View batch COA
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Description

KPV is the tripeptide Lys-Pro-Val, the C-terminal fragment of α-melanocyte-stimulating hormone. Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.

Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile

KPV research profile

KPV is the tripeptide Lys-Pro-Val, the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). It has been studied mainly for its effects on inflammatory signalling in intestinal and skin cell models. Some literature uses the acetylated, amidated form Ac-KPV-NH2, which has a different molecular weight.

Specifications

Sequence
Lys-Pro-Val (KPV), free acid
Molecular formula
C16H30N4O4
Molecular weight
≈ 342.4 g/mol
CAS number
67727-97-3
Size
10MG per vial
Form
Lyophilized powder, sealed vial
Storage
Keep sealed, protected from light and moisture; follow the label
Testing
HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.

Published research

  • Intestinal epithelium: uptake through the PepT1 transporter in intestinal epithelial cells and effects in mouse colitis models (Dalmasso et al., Gastroenterology, 2008).
  • Colitis models: mouse DSS and T-cell-transfer colitis, including MC1R-deficient mice (Kannengiesser et al., Inflamm Bowel Dis, 2008).
  • α-MSH-related peptides: reviewed by Brzoska et al., Endocr Rev, 2008.
  • Skin cells: keratinocytes exposed to fine dust in vitro (Sung et al., Tissue Cell, 2025).
Read the guide KPV: the α-MSH tripeptide explained

Frequently asked questions

Where does KPV come from?

It is the C-terminal tripeptide of α-MSH (Lys-Pro-Val).

Is KPV the same as Ac-KPV-NH2?

No. Ac-KPV-NH2 carries an N-terminal acetyl group and C-terminal amide, so its molecular weight differs from free KPV (≈ 342.4 g/mol). The COA shows which form is in the vial.

How do I verify my lot?

Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.

For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.

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