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Single Peptides
Glutathione
$59.99$0.10/mg
Manufactured in the USA
Lot-tracked production
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Description
Glutathione (GSH) is the tripeptide γ-glutamyl-cysteinyl-glycine, supplied as a research-grade standard. Supplied as a lyophilized powder in sealed vials. For laboratory research use only. Not for human or veterinary use.
Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile
Glutathione research profile
Glutathione (reduced, GSH) is the tripeptide γ-L-glutamyl-L-cysteinylglycine, the most abundant low-molecular-weight thiol in animal cells. Its γ-glutamyl bond resists ordinary peptidases, and its free thiol is oxidized to the disulfide GSSG. Hopkins named it in 1921; its structure was settled in 1929.
Specifications
- Structure
- γ-Glu-Cys-Gly (γ-glutamyl linkage), reduced form
- Molecular formula
- C10H17N3O6S
- Molecular weight
- ≈ 307.3 g/mol
- CAS number
- 70-18-8
- Sizes
- 600 mg and 1500 mg
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Synthesis inhibition: buthionine sulfoximine blocks GSH synthesis (Griffith & Meister, J Biol Chem, 1979).
- Liver models: hepatocyte-specific deletion of the synthesis enzyme Gclc in mice (Chen et al., Hepatology, 2007).
- Detoxification enzymes: glutathione S-transferases reviewed by Hayes et al., 2005.
- Drug-delivery research: GSH-responsive carriers that exploit high intracellular GSH (Cheng et al., 2011).
Frequently asked questions
What is the difference between GSH and GSSG?
GSH is reduced glutathione with a free thiol; GSSG is its oxidized disulfide dimer.
Why is the γ-glutamyl bond important?
Glutamate is linked through its side-chain carboxyl, which makes the bond resistant to ordinary peptidases.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
Save with a bundle
Glutathione is part of these research bundles. See all bundles
Bioregulator series$404.94$329Save $75.94 (19%)Add bundle to cart
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