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100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200
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VIP research vial
COA ON FILEMADE IN USA
Single Peptides

VIP

$59.99$6.00/mg
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Manufactured in the USA
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Description

VIP (vasoactive intestinal peptide) is a 28-amino-acid neuropeptide. Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.

Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile

VIP research profile

VIP (vasoactive intestinal peptide) is a 28-residue, C-terminally amidated neuropeptide of the secretin/glucagon family, acting through the VPAC1 and VPAC2 receptors. Said and Mutt isolated it from pig small intestine in 1970; the sequence is identical in humans, pigs and rats.

Specifications

Sequence
HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 (28 residues)
Molecular formula
C147H238N44O42S
Molecular weight
≈ 3325.8 g/mol
CAS number
40077-57-4
Size
10MG per vial
Form
Lyophilized powder, sealed vial
Storage
Keep sealed, protected from light and moisture; follow the label
Testing
HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.

Published research

  • Discovery and sequence: Said & Mutt, Science, 1970; Mutt & Said, Eur J Biochem, 1974.
  • Exocrine pancreas signalling in isolated acini: VPAC1 and cAMP (Ito et al., Am J Physiol, 2000).
  • Circadian rhythm: VPAC2-knockout mice (Harmar et al., Cell, 2002).
  • Immune regulation: reviewed by Delgado et al., Pharmacol Rev, 2004.

Frequently asked questions

Which receptors does VIP act on?

VPAC1 and VPAC2, class B G-protein-coupled receptors.

Is VIP the same across species?

The 28-residue sequence is identical in humans, pigs and rats.

How do I verify my lot?

Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.

For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.

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