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COA ON FILEMADE IN USA
Capsules
SLU-PP-332 Capsules
$79.99
Description
SLU-PP-332, a synthetic small-molecule ERR ligand, in capsule format for formulation research. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.
Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile
SLU-PP-332 research profile
SLU-PP-332 is a synthetic small molecule (an aryl acylhydrazone, not a peptide) that acts as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ, with the highest potency at ERRα. Its ERR activity was characterized by Billon and colleagues in 2023. The product page address reads "SLU-PP-32", but the compound supplied is SLU-PP-332.
Specifications
- Chemical name
- 4-Hydroxy-N'-(naphthalen-2-ylmethylidene)benzohydrazide
- Molecular formula
- C18H14N2O2
- Molecular weight
- ≈ 290.3 g/mol
- CAS number
- 303760-60-3
- Target
- ERRα / ERRβ / ERRγ agonist (reporter EC50 ≈ 98 / 230 / 430 nM in HEK293 cells)
- Form
- Supplied in capsule format
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Receptor pharmacology and ERRα-dependent gene expression in cultured cells, with oxidative metabolism and treadmill running capacity measured in mice (Billon et al., ACS Chem Biol, 2023).
- Metabolic measures in diet-induced and genetic obesity mouse models, including energy expenditure and fat mass (Billon et al., J Pharmacol Exp Ther, 2024).
- Kidney aging: mitochondrial function and inflammation markers in aged mouse kidney (Wang et al., Am J Pathol, 2023).
- The compound first appears in a 2014 US patent (US 8,680,150) on hematopoietic growth factor mimetics, before its ERR activity was reported.
Frequently asked questions
Is it SLU-PP-32 or SLU-PP-332?
The compound is SLU-PP-332 (CAS 303760-60-3). "SLU-PP-32" is only the page address.
Is SLU-PP-332 a peptide?
No. It is a small molecule with a molecular weight of about 290.3 g/mol.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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