$99.99
This research-grade Vitamin B12 (cobalamin) is intended as a reference material for analytical chemistry, enzymology, and cellular one-carbon metabolism studies. It is not supplied as a dietary supplement.
Cobalamins are cobalt-containing corrinoids that function as essential cofactors in one-carbon transfer reactions and odd-chain fatty acid metabolism.[1] Research-grade B12 is used to standardize assays, evaluate transport and binding proteins, and probe metabolic pathways dependent on methylcobalamin and adenosylcobalamin in vitro and in model organisms.[2,3]
The corrin macrocycle, central cobalt, and exchangeable axial ligands define the redox and catalytic properties of B12 species.[1] Distinct forms (e.g., cyanocobalamin, methylcobalamin) are characterized to assess stability, light sensitivity, and conversion in biological matrices.
Cobalamin-dependent methionine synthase and methylmalonyl-CoA mutase are standard readouts for mechanistic work. Defined B12 concentrations enable kinetic studies, cofactor turnover analysis, and investigation of functional deficiency at the cellular level.[2]
This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.
