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DSIP is a synthetic nonapeptide corresponding to an endogenous peptide first associated with sleep regulation. It is used in neurobiology to investigate sleep–wake modulation, stress responses, and neuroendocrine signaling.
Delta sleep-inducing peptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) has been studied for decades as a putative neuromodulator, with mixed and often conflicting findings regarding its role in sleep induction.[1–3] Modern use is primarily as a tool compound to explore peptide effects on EEG patterns, hypothalamic-pituitary axes, and mitochondrial function under defined conditions.
DSIP’s small size and acidic character enable straightforward synthesis and labeling for receptor/binding studies.[1] It has been detected in several tissues, suggesting complex regulation and potential indirect actions.
Experimental paradigms employ DSIP in animals and cell systems to monitor alterations in sleep architecture, stress hormone secretion, and oxidative phosphorylation.[2,4] Results inform hypotheses about peptide neuromodulation, without constituting validated clinical evidence.
This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.
