Gut Restore

Gut Restore

$139.99

Gut Restore capsules combine 500 mcg BPC-157, 500 mcg KPV, and 1 mg GHK-Cu per capsule. Intended strictly for research use, this formula is examined in models related to epithelial regeneration, peptide-mediated anti-inflammatory signaling, and copper-dependent enzymatic regulation within cellular microenvironments.

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Molecular Overview

BPC-157 (C₆₂H₉₈N₁₆O₂₂) originates from a gastric peptide fragment and is examined for its regulation of cell-matrix interactions.

KPV (Lys-Pro-Val), a tripeptide fragment of α-melanocyte-stimulating hormone, is explored in in-vitro systems for anti-inflammatory peptide signaling.

GHK-Cu (glycyl-L-histidyl-L-lysine-copper(II) complex) is a small copper-binding tripeptide known to modulate gene expression related to matrix remodeling and enzymatic regulation.

Research Applications

1. Epithelial and Barrier Integrity Models

BPC-157 and KPV have both been used in cell culture studies to observe effects on epithelial repair and tight-junction regulation.

These assays help investigate molecular interactions influencing cell proliferation and integrity under peptide exposure.

2. Inflammatory Signaling Pathways

KPV is frequently used as a model peptide in NF-κB and TNF-α pathway studies, enabling exploration of anti-inflammatory peptide mechanisms.

BPC-157 complements this line of study with its capacity to alter growth factor signaling in stressed cell systems.

3. Copper-Dependent Enzymatic Regulation

GHK-Cu has been studied for its metal-ion-mediated regulation of superoxide dismutase and lysyl oxidase in cultured fibroblasts and keratinocytes.

Its inclusion provides a biochemical model for copper-dependent cellular signaling in peptide research.

4. Gene Expression and Proteomic Analysis

The triple-peptide combination presents opportunities to examine transcriptional networks and matrix gene activation relevant to regenerative biology without implying therapeutic use.

Referenced Citations

  1. PubChem CID 9941957 – BPC-157
  2. PubChem CID 5462286 – KPV (Lys-Pro-Val)
  3. PubChem CID 5311446 – GHK-Cu (Gly-His-Lys Copper)
  4. PubMed ID 29909858 – “BPC-157 in epithelial cell cultures: structural regulation” (Acta Pharmacol Sin)
  5. PubMed ID 17920248 – “KPV peptide and epithelial cytokine modulation” (Am J Physiol Cell Physiol)
  6. PubMed ID 28797702 – “KPV and melanocortin signaling in inflammation models” (J Immunol Res)
  7. PubMed ID 30613421 – “GHK-Cu peptide regulates copper enzymes in fibroblast models” (Mol Cell Biochem)
  8. PubMed ID 20828225 – “GHK-Cu and gene expression patterns in peptide-treated cells” (BBA Gen Subj)

Product Usage:

This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.