TB-500 Capsules
TB-500 Capsules - Image 2

TB-500 Capsules

$89.99

TB-500 (Thymosin Beta-4 fragment) is a synthetic peptide widely studied for its role in cellular migration, angiogenesis, and tissue remodeling processes. Supplied here in capsule form for laboratory use only, TB-500 offers researchers a consistent, high-purity material for controlled studies across molecular biology, regenerative sciences, and cellular signaling pathways.

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Research Applications of TB-500

  1. Cellular Migration and Cytoskeletal Dynamics

TB-500 is derived from the naturally occurring peptide Thymosin Beta-4, which plays a crucial role in actin binding and cytoskeletal organization. Studies have demonstrated its involvement in cell motility, influencing endothelial cells, keratinocytes, and fibroblasts [1]. This makes it valuable for laboratory research into wound healing models, angiogenesis, and cell migration mechanisms.

  1. Angiogenesis and Vascular Biology

Research has shown TB-500 to be a potent regulator of angiogenesis. It stimulates endothelial progenitor cells and vascular endothelial growth factor (VEGF) pathways, thereby supporting blood vessel formation in experimental systems [2]. Such findings provide a foundation for its use in studying vascular biology and ischemic models at a cellular and molecular level.

  1. Regenerative Biology and Tissue Repair Models

TB-500 has been studied extensively in the context of tissue regeneration, with evidence of enhanced repair in corneal, dermal, and cardiac tissues in controlled settings [3]. Its role in orchestrating extracellular matrix remodeling and cell differentiation makes it a strong candidate for regenerative biology research.

  1. Anti-Inflammatory Mechanisms

Laboratory research suggests TB-500 modulates inflammatory responses by downregulating pro-inflammatory cytokines and promoting anti-inflammatory mediators [4]. This area of study has drawn interest in fields such as immunology, neuroinflammation, and chronic injury modeling.

  1. Neurological Research

Emerging studies indicate that TB-500 may influence neurogenesis and axonal growth, which are relevant to experimental models of central nervous system injury [5]. These effects are still under investigation, but they broaden the scope of TB-500 into neuroscience research.

Referenced Citations:

  1. Huff, T. et al. (2001). The role of thymosin β4 in actin binding and cell motility. Journal of Biological Chemistry. PubMed
  2. Malinda, K. M. et al. (1997). Thymosin β4 stimulates endothelial cell migration. FASEB Journal. PubMed
  3. Smart, N. et al. (2007). Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization. Nature. PubMed
  4. Sosne, G. et al. (2010). Thymosin β4 suppresses inflammation in experimental models. Investigative Ophthalmology & Visual Science. PubMed
  5. Morris, D. C. et al. (2010). Thymosin β4 promotes axonal regeneration and neuroprotection. Journal of Neuroscience Research. PubMed

Product Usage:

This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.