$79.99
GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II), PubChem CID: 5311433) is a naturally occurring tripeptide–copper complex supplied for laboratory investigation only. It is commonly studied for its roles in extracellular matrix remodeling, copper transport, oxidative stress response, and cellular signaling. Provided in high purity, it is strictly intended for in vitro research applications.
GHK-Cu is the copper(II) chelate of the tripeptide glycyl-histidyl-lysine. PubChem records its molecular formula as C14H24CuN6O4 and molecular weight ~340.9 g/mol [1]. Its structure enables high-affinity binding of Cu²⁺ ions, stabilizing the tripeptide and supporting biochemical studies of metal–peptide interactions.
As a copper-binding complex, GHK-Cu facilitates laboratory modeling of copper transport and distribution. PubChem annotations note its use in experimental systems studying lysyl oxidase activity, superoxide dismutase regulation, and copper-dependent enzymatic pathways [1]. These studies help clarify metal-ion bioavailability and metalloprotein activation.
PubChem literature links describe the peptide’s ability to modulate extracellular matrix metabolism [1]. In vitro assays frequently measure collagen synthesis, fibronectin expression, and matrix metalloproteinase activity following GHK-Cu exposure. Researchers employ these endpoints to better understand tissue remodeling, fibrosis models, and controlled wound-healing pathways.
Through copper coordination, GHK-Cu contributes to studies of redox balance and reactive oxygen species (ROS) regulation. PubChem cites related antioxidant activity, allowing its use in mechanistic investigations of oxidative stress response and cellular defense against free radicals in controlled model systems [1].
Experimental evidence aggregated in PubChem demonstrates GHK-Cu’s effects on transcriptional networks related to growth factors, angiogenesis mediators, and inflammatory cytokines [1]. This makes it a useful chemical probe for evaluating copper-mediated signal transduction in cultured cells, without implying therapeutic use.
GHK-Cu is a PubChem-indexed copper tripeptide complex of glycyl-histidyl-lysine with robust roles in copper transport, ECM remodeling, redox regulation, and cell signaling. Its precise chemical identity ensures reproducibility in laboratory studies, supporting mechanistic work in extracellular matrix biology and metal-ion research. It is intended strictly for scientific research [1].
This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.
