AOD-9604
AOD-9604 - Image 2
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AOD-9604

$49.99

AOD-9604 is a synthetic peptide fragment of human growth hormone (hGH), comprising amino acids 176–191. Designed to focus on fat metabolism without affecting IGF-1 or glucose levels, it is widely studied in metabolic and obesity-related research. AOD-9604 is intended exclusively for controlled laboratory use in scientific research.

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Product Overview:

Product Name: AOD-9604
Quantity: 10mg
Molecular Formula: C78H123N23O23S2
Molecular Weight: ~1815.1 g/mol
Research Use Only. Not for Human Consumption.

Research Applications:

  1. Metabolic and Lipolytic Regulation

AOD-9604 was developed by modifying the C-terminal segment (176–191) of human growth hormone (hGH). This region is believed to be responsible for hGH’s fat-reducing effects. Studies show AOD-9604 can stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation) in vitro without exerting significant effects on blood sugar or insulin sensitivity [1].

Its selective activation of lipolytic pathways without impacting IGF-1 makes it an important compound for researchers studying energy balance and fat metabolism mechanisms [2]. These features allow AOD-9604 to be studied in models where hGH-related mitogenic or diabetogenic effects are undesirable.

  1. Obesity and Adipose Tissue Models

In preclinical models, especially in obese rodents, AOD-9604 has demonstrated the ability to reduce body fat mass without altering lean muscle or organ weights [3]. It shows preferential activity on visceral adipose tissues and has been observed to enhance lipid mobilization even in high-calorie diet models. Importantly, this effect appears to occur independently of pituitary axis signaling, which distinguishes it from unmodified hGH.

This specificity makes AOD-9604 of interest in research focused on obesity, adipocyte biology, and endocrine-independent fat regulation pathways.

  1. Safety Profile in Preclinical Settings

According to animal studies and toxicological reviews, AOD-9604 did not exhibit mitogenic activity or increase in IGF-1 levels [4], key concerns often associated with full-length growth hormone analogs. These findings support its use in studies requiring metabolic modulation with reduced risk of off-target cellular proliferation.

Referenced Citations:

  1. Heffernan M, et al. “The metabolic effects of hGH fragment 176–191.”PubMed
    Source: Peptides Journal – Examines lipid metabolism in animal models.
  2. Ng FM, et al. “Lipolytic action of hGH 176–191 fragment in adipocytes.” PubMed
    Source: Journal of Endocrinology – Demonstrates direct stimulation of fat breakdown.
  3. Hoffman DM, et al. “Development and pharmacodynamics of AOD9604.” PubMed
    Source: Clinical Endocrinology – Details pharmacological profile in preclinical models.
  4. Pharmacological Review: AOD-9604 safety in animal models – PubChem CID: 9853787
    Source: PubChem – Safety and structure profile.

Product Usage:

This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.