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100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200
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Kisspeptin research vial
COA ON FILEMADE IN USA
Single Peptides

Kisspeptin

$59.99$6.00/mg
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Manufactured in the USA
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Description

Kisspeptin-10 is a synthetic decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2). Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.

Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile

Kisspeptin-10 research profile

Kisspeptin-10 is the C-terminal decapeptide of kisspeptin-54 (metastin), the peptide products of the KISS1 gene. It is the minimal sequence that activates the GPR54 (KISS1R) receptor. Metastin was isolated from human placenta by Ohtaki and colleagues at Takeda in 2001.

Specifications

Sequence
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2)
Molecular formula
C63H83N17O14
Molecular weight
≈ 1302.5 g/mol
CAS number
374675-21-5
Size
10MG per vial
Form
Lyophilized powder, sealed vial
Storage
Keep sealed, protected from light and moisture; follow the label
Testing
HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.

Published research

  • Discovery and metastasis: CHO cell migration and B16-BL6 melanoma lung metastasis in mice (Ohtaki et al., Nature, 2001); kisspeptins named as GPR54 ligands (Kotani et al., J Biol Chem, 2001).
  • Chemotaxis signalling: Kp-10/GPR54 and CXCR4-mediated migration (Navenot et al., Cancer Res, 2005).
  • GnRH neuron physiology in mouse brain slices (Pielecka-Fortuna et al., Endocrinology, 2008).
  • Reproductive-axis physiology studies (George et al., J Clin Endocrinol Metab, 2011).

Frequently asked questions

What is the difference between kisspeptin-10 and kisspeptin-54?

Kisspeptin-54 (metastin) is the full 54-residue peptide; kisspeptin-10 is its last 10 residues, the minimal sequence that activates GPR54.

Why is it called metastin?

The KISS1 gene was first known as a metastasis suppressor.

How do I verify my lot?

Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.

For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.

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