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Sprays
NAD+ Spray
$64.99
Manufactured in the USA
Lot-tracked production
Protective packaging
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Description
NAD+ (nicotinamide adenine dinucleotide) in a buffered aqueous solution. Supplied in a spray bottle. For laboratory research use only. Not for human or veterinary use.
Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile
NAD+ research profile
NAD+ (β-nicotinamide adenine dinucleotide, oxidized form) is a dinucleotide coenzyme in which nicotinamide riboside and adenosine are joined through a pyrophosphate bridge. Harden and Young first described it in yeast in 1906. It is a substrate for sirtuins and PARPs as well as a redox carrier.
Specifications
- Structure
- Nicotinamide riboside and adenosine linked by pyrophosphate
- Molecular formula
- C21H27N7O14P2 (free acid)
- Molecular weight
- ≈ 663.4 g/mol (free acid)
- CAS number
- 53-84-9
- Sizes
- 500 mg and 1000 mg
- Form
- Supplied in spray format
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Sirtuin biology: NAD+ as the required substrate of Sir2 proteins in yeast and mouse (Imai et al., Nature, 2000).
- Age-related decline: nuclear–mitochondrial signalling in young vs old mice (Gomes et al., Cell, 2013).
- CD38 as a driver of NAD+ decline with age in mice (Camacho-Pereira et al., Cell Metab, 2016).
- Precursor studies: NMN in mouse models of diet- and age-induced diabetes (Yoshino et al., Cell Metab, 2011).
Frequently asked questions
What is the difference between NAD+ and NADH?
NAD+ is the oxidized form; NADH is the reduced form carrying a hydride.
Why do salt forms matter?
The CAS number and molecular weight above are for the free acid; salts and hydrates differ. The COA lists what was tested.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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