Semax Spray
Semax, a synthetic heptapeptide, in a buffered aqueous solution. Supplied in a spray bottle. For laboratory research use only. Not for human or veterinary use.
Semax research profile
Semax is a synthetic heptapeptide built from the ACTH(4–7) fragment (Met-Glu-His-Phe) extended with Pro-Gly-Pro, a motif associated with greater resistance to peptidase breakdown. It was developed in Russia and first appears in the literature in 1991; most of its research comes from Russian laboratories.
Specifications
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
- Molecular formula
- C37H51N9O10S
- Molecular weight
- ≈ 813.9 g/mol
- CAS number
- 80714-61-0
- Form
- Supplied in spray format
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Neurotrophin expression: BDNF and TrkB in rat hippocampus (Dolotov et al., Brain Res, 2006).
- Monoamine systems: dopaminergic and serotonergic measures in rodents (Eremin et al., Neurochem Res, 2005).
- Stress models: rat chronic unpredictable stress (Yatsenko et al., Dokl Biol Sci, 2013).
- Receptor pharmacology and metabolism: melanocortin receptor work (Bertolini, Eur J Pharmacol, 2012); degradation by rat blood enzymes (Potaman et al., BBRC, 1991).
Frequently asked questions
What is Semax derived from?
The ACTH(4–7) fragment, Met-Glu-His-Phe, with a Pro-Gly-Pro tail added.
How is Semax related to Adamax?
Adamax is described as a Semax-family analog with terminal modifications. See our Adamax and Semax guide.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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