Crystagen
Crystagen is a synthetic tripeptide bioregulator (Glu-Asp-Pro). Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.
Crystagen research profile
Crystagen (also spelled Cristagen) is the name used for the synthetic tripeptide Glu-Asp-Pro (EDP). It was developed by V. Kh. Khavinson's group, and EDP has been reported as a minor component of thymalin, a polypeptide complex isolated from calf thymus. Published work covers tissue explants, cell cultures, rodent models and molecular docking.
Specifications
- Sequence
- Glu-Asp-Pro (EDP)
- Molecular formula
- C14H21N3O8
- Molecular weight
- ≈ 359.3 g/mol
- Size
- 20MG per vial
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Thymus and spleen explants from 24-month-old rats, peritoneal macrophages from aging mice, a thymic epithelial cell line and a radiation-induced premature-aging rat model are described in the developers' patent (Khavinson et al., US Patent 8,057,810, 2011).
- Analytical chemistry: EDP and KE identified by UPLC-MS as minor components of the calf-thymus preparation thymalin (Khavinson et al., Molekulyarnaya Meditsina, 2021).
- Molecular docking: EDP modelled binding to the DNA sequence agat, with an extra hydrogen bond compared with KE (Khavinson, Lin'kova & Tarnovskaya, Bull Exp Biol Med, 2016).
- Note: peer-reviewed literature on this sequence is limited and comes mostly from one research group.
Frequently asked questions
Is it Crystagen or Cristagen?
Both spellings are used for the same tripeptide, Glu-Asp-Pro (EDP).
What is the molecular weight of Crystagen?
About 359.3 g/mol for the free tripeptide, consistent with the 359.33 value given in the developers' patent.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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