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100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200
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Pinealon research vial
COA ON FILEMADE IN USA
Bioregulators

Pinealon

$59.99$3.00/mg
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Manufactured in the USA
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Description

Pinealon is a synthetic tripeptide bioregulator (Glu-Asp-Arg). Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.

Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile

Pinealon research profile

Pinealon is the synthetic tripeptide Glu-Asp-Arg (EDR), developed by V. Kh. Khavinson's group. It is one of the more widely published short bioregulator peptides, with studies in neuronal and other cell cultures, rat models and DNA-binding modelling.

Specifications

Sequence
Glu-Asp-Arg (EDR)
Molecular formula
C15H26N6O8
Molecular weight
≈ 418.4 g/mol
CAS number
175175-23-2
Size
20MG per vial
Form
Lyophilized powder, sealed vial
Storage
Keep sealed, protected from light and moisture; follow the label
Testing
HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.

Published research

  • Oxidative stress in cell culture: reactive oxygen species, necrotic cell death and ERK1/2 activation in rat cerebellar granule cells, neutrophils and PC12 cells (Khavinson et al., Rejuvenation Res, 2011).
  • Rat model of prenatal hyperhomocysteinemia: oxidative and neuronal measures in the offspring (Arutjunyan et al., Int J Clin Exp Med, 2012).
  • Dendritic spines: mushroom-spine counts in primary mouse hippocampal neurons under amyloid synaptotoxicity (Kraskovskaya et al., Bull Exp Biol Med, 2017); spine counts in the 5xFAD mouse model with DNA-docking analysis of gene promoters (Khavinson et al., Pharmaceuticals, 2021).
  • Serotonin expression in brain cortex cell cultures (Khavinson et al., Bull Exp Biol Med, 2014).
  • Review of proposed gene-expression and protein-synthesis mechanisms (Khavinson et al., Molecules, 2020).
Read the guide Short peptide bioregulators: an overview for researchers

Frequently asked questions

What is the sequence of Pinealon?

Glu-Asp-Arg (EDR), a tripeptide with a molecular weight of about 418.4 g/mol.

Is Pinealon the same as Epitalon?

No. Pinealon is the tripeptide EDR; Epitalon is the tetrapeptide AEDG. Both come from the same research group.

How do I verify my lot?

Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.

For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.

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