Vilon
Vilon is a synthetic dipeptide bioregulator (Lys-Glu). Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.
Vilon research profile
Vilon is the synthetic dipeptide Lys-Glu (KE), developed by V. Kh. Khavinson's group and described as a component of the thymus preparation thymalin. It is among the earliest of the group's synthetic short peptides, studied in lifelong mouse experiments, lymphocyte cultures and gene-expression work.
Specifications
- Sequence
- Lys-Glu (KE)
- Molecular formula
- C11H21N3O5
- Molecular weight
- ≈ 275.3 g/mol
- Size
- 20MG per vial
- Form
- Lyophilized powder, sealed vial
- Storage
- Keep sealed, protected from light and moisture; follow the label
- Testing
- HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.
Published research
- Aging-biomarker studies in female CBA mice from 6 months of age: physical activity, body temperature, estrous function, free-radical measures, spontaneous tumour incidence and survival (Khavinson & Anisimov, Bull Exp Biol Med, 2000; Anisimov et al., Mech Ageing Dev, 2001).
- Aging cell cultures: skin fibroblast Ki-67, CD98hc and MMP-9 (Lin'kova et al., Bull Exp Biol Med, 2016) and gene expression in human mesenchymal stem cells (Ashapkin et al., Mol Biol Rep, 2020).
- Analytical chemistry: KE identified by UPLC-MS as a minor component of thymalin (Khavinson et al., Molekulyarnaya Meditsina, 2021).
- Review of experimental work on KE and related peptides, including lymphocyte and thymocyte cultures and irradiated-rat models (Khavinson, Kuznik & Ryzhak, Adv Gerontol, 2013).
Frequently asked questions
What is the sequence of Vilon?
Lys-Glu (KE), a dipeptide with a molecular weight of about 275.3 g/mol.
How does Vilon relate to thymalin?
Thymalin is a polypeptide complex isolated from calf thymus. KE has been identified in it as a minor component by mass spectrometry.
How do I verify my lot?
Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.
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