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100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200100% manufactured in the USABatch-specific COAs on tested lots76 research compounds in stockFor research use onlyFree shipping on orders over $200
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Cardiogen research vial
COA ON FILEMADE IN USA
Bioregulators

Cardiogen

$59.99$3.00/mg
Size
Manufactured in the USA
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Description

Cardiogen is a synthetic short-chain tetrapeptide bioregulator (Ala-Glu-Asp-Arg). Supplied as a lyophilized powder in sealed vials. Each batch has its own certificate of analysis (COA), which opens when you scan the QR code on the label. For laboratory research use only. Not for human or veterinary use.

Research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease.
Research profile

Cardiogen research profile

Cardiogen is the name used for the synthetic tetrapeptide Ala-Glu-Asp-Arg (AEDR), developed by V. Kh. Khavinson's group. Published work includes rat cardiac and tumour models, isolated-heart preparations and cardiac tissue explants, much of it described in the developers' patent.

Specifications

Sequence
Ala-Glu-Asp-Arg (AEDR)
Molecular formula
C18H31N7O9
Molecular weight
≈ 489.5 g/mol
Size
20MG per vial
Form
Lyophilized powder, sealed vial
Storage
Keep sealed, protected from light and moisture; follow the label
Testing
HPLC purity and mass spectrometry identity, per lot. Scan the QR code on the vial for the certificate of analysis.

Published research

  • Rat coronary ligation, isolated perfused rat and guinea-pig hearts, adrenaline-induced myocardial dystrophy and cardiac organotypic explants are described in the developers' patent (Khavinson et al., US Patent 7,662,789, 2010).
  • Tumour model: apoptosis, proliferative activity and tumour growth of transplanted M-1 sarcoma in senescent rats (Levdik & Knyazkin, Bull Exp Biol Med, 2009).
  • Listed as AEDR (Cardiogen) among the group's short peptides in a review of peptide regulation of gene expression (Khavinson, Lin'kova & Tarnovskaya, Bull Exp Biol Med, 2016).
  • Note: the literature comes mostly from one research group.
Read the guide Short peptide bioregulators: an overview for researchers

Frequently asked questions

What is the sequence of Cardiogen?

Ala-Glu-Asp-Arg (AEDR), a tetrapeptide with a calculated molecular weight of about 489.5 g/mol.

How is Cardiogen related to Pinealon?

Cardiogen (AEDR) contains the Pinealon sequence (EDR) with an alanine added at the N-terminus.

How do I verify my lot?

Scan the QR code on the vial. It opens the certificate of analysis for that lot, with HPLC purity and the mass spectrometry identity result.

For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Literature references are provided for scientific context and do not describe this product's suitability for any use.

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